Primitive neuroectodermal tumor
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Primitive Neuroectodermal Tumors, or PNET, refers to two different tumor types. These include Peripheral PNET and CNS PNET. This can be a source of confusion.
Some PNET Types
Peripheral PNET
The Peripheral PNET is now thought to be virually identical to Ewing sarcoma:
"Current evidence indicates that both Ewing's sarcoma and PNET have a similar neural phenotype and, because they share an identical chromosome translocation, they should be viewed as the same tumor, differing only in their degree of neural differentiation. Tumors that demonstrate neural differentiation by light microscopy, immunohistochemistry, or electron microscopy have been traditionally labeled PNETs, and those that are undifferentiated by these analyses have been diagnosed as Ewing's sarcoma." [1]
PNET of the CNS
PNET of the CNS are grossly divided into supratentorial PNET and infratentorial PNET, the latter being more common. [2]
An example of infratentorial PNET includes Medulloblastomas, which occurs in the cerebellum.
An example of supratentorial PNET includes Pinealoblastomas, which occurs in the pineal region.
References
- ↑ Robbins Pathologic Basis of Disease, 7th edition
- ↑ Subrata Ghosh, MD, MBBS, MS, Primitive Neuroectodermal Tumors of the Central Nervous System, eMedicine 2007.
References
<biblio>
</biblio>
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.
Initial content for this page in some instances came from Wikipedia
List of contributors:
Suggested Reading and Key General References
Suggested Links and Web Resources
For Patients
de:Primitiv neuroektodermaler Tumor
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
