Proglumetacin

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

Jump to: navigation, search
Image:Proglumetacin.svg
Proglumetacin
Systematic (IUPAC) name
3-[4-[2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-
methylindol-3-yl]acetyl]oxyethyl]piperazin-1-yl]
propyl 4-(benzoylamino)-5-(dipropylamino)-
5-oxopentanoate
Identifiers
CAS number 57132-53-3
59209-40-4 (maleate)
ATC code M01AB14
PubChem 4921
Chemical data
Formula C46H58ClN5O8 
Mol. mass 844.43442 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic. Undergoes enterohepatic recirculation
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide,[1] a drug with antisecretory effects that helps prevent injury to the stomach lining.

References


Personal tools