Prolactin receptor
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| prolactin receptor
| |
| Identifiers | |
| Symbol | PRLR |
| Entrez | 5618 |
| HUGO | 9446 |
| OMIM | 176761 |
| RefSeq | NM_000949 |
| UniProt | P16471 |
| Other data | |
| Locus | Chr. 5 p13-p12 |
The prolactin receptor—encoded by a gene on Chromosome 5p13-14—interacts with the prolactin molecule as a transmembrane receptor.
Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region.
A specific second messenger has not yet been identified.
There may be variations among different tissue prolactin receptors.
External links
Neuropeptide receptors | |
|---|---|
| Hypothalamic hormone receptors | CRH - FSH - LHRH - TRH - Somatostatin |
| Pituitary hormone receptors | Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - Type I cytokine receptor (GH, Prolactin) - TSH |
| Other hormone receptors | Atrial natriuretic factor - Calcitonin - Cholecystokinin (A, B) - VIP |
| Opioid receptors | Delta - Kappa - Mu - Sigma (1, 2) - Nociceptin |
| Other neuropeptide receptors | Angiotensin - Bradykinin (B1, B2) / Tachykinin (TACR1) - Calcitonin gene-related peptide - Galanin - GPCR neuropeptide (B/W, FF, S, Y) - Neurotensin |
