Prostaglandin D2 synthase

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prostaglandin D2 synthase 21kDa (brain)
Identifiers
Symbol	PTGDS
Entrez	5730
HUGO	9592
OMIM	176803
RefSeq	NM_000954
UniProt	P41222
Other data
EC number	5.3.99.2
Locus	Chr. 9 q34.2-34.3

Prostaglandin D2 synthase generates prostaglandin D2 from prostaglandin H2.

v • d • e Intramolecular oxidoreductases isomerases (EC 5.3)
5.3.1 - Aldoses/Ketoses	Triosephosphate isomerase - Phosphopentose isomerase - Mannose phosphate isomerase - Glucose isomerase
5.3.3 - C=C	Isopentenyl-diphosphate delta isomerase - Enoyl CoA isomerase
5.3.4 - S-S	Protein disulfide isomerase (PDIA3)
5.3.99 - other	Prostaglandin D2 synthase - Prostaglandin E synthase - Prostacyclin synthase - Thromboxane-A synthase

v • d • e Metabolism: lipid metabolism
Lipid production	Acetyl-CoA carboxylase - Fatty acid synthesis: Beta-ketoacyl-ACP synthase - Β-Ketoacyl ACP reductase - 3-Hydroxyacyl ACP dehydrase - Enoyl ACP reductase unsaturated (Enoyl CoA isomerase, 2,4 Dienoyl-CoA reductase) - odd chain (Propionyl-CoA carboxylase) - Fatty acid synthase - Long fatty acyl CoA synthetase
Lipid degradation	Acyl transport: Carnitine palmitoyltransferase I - Carnitine-acylcarnitine translocase - Carnitine palmitoyltransferase II Beta oxidation: Acyl CoA dehydrogenase (ACADL, ACADM, ACADS, ACADVL) - Enoyl-CoA hydratase - 3-Hydroxyacyl CoA dehydrogenase - Acetyl-CoA C-acyltransferase - Mitochondrial trifunctional protein Ketogenesis: HMG-CoA synthase - HMG-CoA lyase - Other: Malonyl-CoA decarboxylase
Phospholipids	Diacylglycerol kinase
Steroids	HMG-CoA reductase - Farnesyl-diphosphate farnesyltransferase - Squalene monooxygenase - Lanosterol synthase - CYP51A1
Prostanoids	Cyclooxygenase - Thromboxane-A synthase - Prostacyclin synthase - Prostaglandin E synthase - Prostaglandin D2 synthase
Leukotrienes	Arachidonate 5-lipoxygenase - 5-Lipoxygenase activating protein - Leukotriene A4 hydrolase - Leukotriene C4 synthase
Bile acids	Cholesterol 7 alpha-hydroxylase