Protein electrophoresis

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WikiDoc Resources for Protein electrophoresis
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Evidence Based Medicine
Cochrane Collaboration on Protein electrophoresis Bandolier on Protein electrophoresis TRIP on Protein electrophoresis
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Definitions of Protein electrophoresis
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In chemistry and medicine, protein electrophoresis is a method of analysing a mixture of proteins by means of gel electrophoresis, mainly in blood serum (blood plasma is not suitable).

Interpretation

There are two large classes of blood proteins: serum albumin and globulin. They are generally equal in proportion, but albumin is much smaller and lightly negatively charged, leading to an accumulation of albumin on the electrophoretic gel. A small band before albumin represents transthyretin (also named prealbumin). Some forms of medication or body chemicals can cause their own band, usually small. Abnormal bands are seen in monoclonal gammopathy of undetermined significance and multiple myeloma, and are useful in the diagnosis of these conditions.

The globulins are classified by their banding pattern (with their main representatives):

• The alpha (α) band consists of two parts, 1 and 2:
  • α₁ - α₁-antitrypsin, α₁-acid glycoprotein.
  • α₂ - haptoglobin, α₂-macroglobulin, α₂-antiplasmin, ceruloplasmin.
• The beta (β) band - transferrin, LDL, complement
• The gamma (γ) band - immunoglobulin (IgA, IgD, IgE, IgG and IgM). Paraproteins (in multiple myeloma) appear in this band.

See also

• Gel electrophoresis
• Paraprotein
• Electrofocusing
• QPNC-PAGE

v • d • e Proteins: key methods of study
Experimental	Protein purification - Green fluorescent protein - Western blot - Protein immunostaining - Protein sequencing - Gel electrophoresis/Protein electrophoresis - Protein immunoprecipitation - Peptide mass fingerprinting
Bioinformatics	Protein structure prediction - Protein-protein docking - Protein structural alignment - Protein ontology - Protein-protein interaction prediction
Assay	Enzyme assay - Protein assay - Secretion assay

v • d • e WikiDoc Research Resources for Protein electrophoresis (Click show to right to view)
Articles on Protein electrophoresis	Most recent articles on Protein electrophoresis • Most cited articles on Protein electrophoresis • Review articles on Protein electrophoresis • Articles on Protein electrophoresis in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Protein electrophoresis	Powerpoint slides on Protein electrophoresis • Images of Protein electrophoresis • Photos of Protein electrophoresis • Podcasts & MP3s on Protein electrophoresis • Videos on Protein electrophoresis
Evidence Based Medicine Regarding Protein electrophoresis	Cochrane Collaboration on Protein electrophoresis • Bandolier on Protein electrophoresis • TRIP on Protein electrophoresis
Cost Effectiveness of Protein electrophoresis	Cost Effectiveness of Protein electrophoresis
Clinical Trials Involving Protein electrophoresis	Ongoing Trials on Protein electrophoresis at Clinical Trials.gov • Trial results on Protein electrophoresis • Clinical Trials on Protein electrophoresis at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Protein electrophoresis	US National Guidelines Clearinghouse on Protein electrophoresis • NICE Guidance on Protein electrophoresis • NHS PRODIGY Guidance • FDA on Protein electrophoresis • CDC on Protein electrophoresis
Textbook Information on Protein electrophoresis	Books and Textbook Information on Protein electrophoresis
Pharmacology Resources on Protein electrophoresis	Dosing of Protein electrophoresis • Drug interactions with Protein electrophoresis • Side effects of Protein electrophoresis • Allergic reactions to Protein electrophoresis • Overdose information on Protein electrophoresis • Carcinogenicity information on Protein electrophoresis • Protein electrophoresis in pregnancy • Pharmacokinetics of Protein electrophoresis •
Genetics, Pharmacogenomics, and Proteinomics of Protein electrophoresis	Genetics of Protein electrophoresis • Pharmacogenomics of Protein electrophoresis • Proteomics of Protein electrophoresis
Newstories on Protein electrophoresis	Protein electrophoresis in the news • Be alerted to news on Protein electrophoresis • News trends on Protein electrophoresis
Commentary on Protein electrophoresis	Blogs on Protein electrophoresis
Patient Resources on Protein electrophoresis	Patient resources on Protein electrophoresis • Discussion groups on Protein electrophoresis • Patient Handouts on Protein electrophoresis • Directions to Hospitals Treating Protein electrophoresis • Risk calculators and risk factors for Protein electrophoresis
Healthcare Provider Resources on Protein electrophoresis	Symptoms of Protein electrophoresis • Causes & Risk Factors for Protein electrophoresis • Diagnostic studies for Protein electrophoresis • Treatment of Protein electrophoresis
Continuing Medical Education (CME) Programs on Protein electrophoresis	CME Programs on Protein electrophoresis
International Resources on Protein electrophoresis	Protein electrophoresis en Espanol • Protein electrophoresis en Francais
Business Resources on Protein electrophoresis	Protein electrophoresis in the Marketplace • Patents on Protein electrophoresis
Informatics Resources on Protein electrophoresis	List of terms related to Protein electrophoresis

fr:Électrophorèse des protéines

de:Serumelektrophorese

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .