Pyridoxine (patient information)

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Why this medication is prescribed

Pyridoxine, vitamin B6, is required by your body for utilization of energy in the foods you eat, production of red blood cells, and proper functioning of nerves. It is used to treat and prevent vitamin B6deficiency resulting from poor diet, certain medications, and some medical conditions.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used

Pyridoxine comes in regular and extended-release (long-acting) tablets. It usually is taken once a day. Follow the directions on your prescription label or package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take pyridoxine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not chew, crush, or cut extended-release tablets; swallow them whole.

Special Precautions

Before taking pyridoxine:

  • tell your doctor and pharmacist if you are allergic to pyridoxine or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially levodopa (Larodopa, Sinemet), phenobarbital, phenytoin (Dilantin), and other vitamins.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking pyridoxine, call your doctor.

Special dietary instructions

Your doctor may tell you to eat more foods containing vitamin B6, especially whole-grain cereals, fish, vegetables, beans, and liver and other organ meat.

What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side Effects

Minor Side Effects

Pyridoxine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • upset stomach
  • headache
  • sleepiness
  • tingling, prickling, burning, or sensation of tightness of the hands and feet

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to pyridoxine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

  • Nestrex®

Other names

  • Vitamin B6


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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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