Rolf M. Zinkernagel
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Rolf Martin Zinkernagel (January 6, 1944 in Riehen, Basel-Stadt, Switzerland) is Professor of Experimental Immunology at the University of Zurich.
Together with the Australian Peter C. Doherty he received the 1996 Nobel Prize in Physiology or Medicine for the discovery of how the immune system recognizes virus-infected cells. With this he became the 24th Swiss Nobel laureate.
Viruses infect host cells and reproduce inside them. Killer T-cells destroy those infected cells so that the viruses can't reproduce. Zinkernagel and Doherty discovered that, in order for killer T cells to recognize infected cells, they had to recognize two molecules on the surface of the cell -- not only the virus antigen, but also a molecule of the major histocompatibility complex (MHC). This recognition was done by a T-cell receptor on the surface of the T cell. The MHC was previously identified as being responsible for the rejection of incompatible tissues during transplantation. Zinkernagel and Dougherty discovered that the MHC was responsible for the body fighting meningitis viruses too. [1]
He received his MD from the University of Basel in 1970 and his PhD from the Australian National University in 1975. In addition to the Nobel Prize, he also won The Albert Lasker Medical Research Award in 1995.
References
External links
Template:BDca:Rolf Martin Zinkernagel de:Rolf Zinkernagel[[hr:Rolf M. Zinkernagel fr:Rolf M. Zinkernagel hr:Rolf M. Zinkernagel id:Rolf M. Zinkernagel ja:ロルフ・ツィンカーナーゲルsv:Rolf M. Zinkernagel
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
