Rosalyn Sussman Yalow

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[[Image:Image:Replace this image female.svg|300px| ]] Rosalyn Sussman Yalow
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Data 2:	July 19 1921 (1921-07-19) (age 87) New York City, New York
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Overview

Rosalyn Sussman Yalow (born July 19, 1921) is an American medical physicist, and a co-winner of the 1977 Nobel Prize in Physiology or Medicine for her development of the radioimmunoassay (RIA) technique.

Biography

Born Rosalyn Sussman in New York City to Simon Sussman and Clara Zipper, Dr. Yalow attended Walton High School and graduated in 1941 from Hunter College, where she developed an interest in physics.

As she knew how to type, she obtained a part time position as secretary to Dr. Rudolf Schoenheimer, a leading biochemist at Columbia University's College of Physicians and Surgeons. Not believing that any good graduate school would admit and provide financial support to a woman Sussman studied stenography and took a job as a secretary to Michael Heidelberger, another biochemist at Columbia. She graduated from Hunter College in January 1941.

In mid-February she received an offer of a teaching assistantship in physics at the University of Illinois at Urbana-Champaign because World War II came up and many men went off to war and the university offered scholarships for women rather than close down. That summer she took two tuition-free physics courses under government auspices at New York University. At the University of Illinois, she was the only woman among the department's 400 members, and the first since 1917. She married fellow student Aaron Yalow in 1943, and received her Ph.D. in 1945. After graduating, Yalow joined the Bronx Veterans Administration Hospital to help set up its radioisotope service. There she collaborated with Solomon Berson to develop RIA, a radioisotope tracing technique that allows the measurement of tiny quantities of various biological substances in the blood. Originally used to study insulin levels in diabetes mellitus,^[1] the technique has since been applied to hundreds of other substances – including hormones, vitamins and enzymes – all previously too small to detect. Despite its huge commercial potential, Yalow and Berson refused to patent the method.

In 1975 Yalow and Berson received the AMA Scientific Achievement Award. The following year she became the first female recipient of the Albert Lasker Award for Basic Medical Research. In 1977 she received the Nobel Prize, together with Roger Guillemin and Andrew V. Schally. Berson had died in 1972, and so could not share the latter prizes. She received the National Medal of Science in 1988.

Dr. Yalow still lives in the same house in Riverdale, Bronx, New York that she bought when she first began working at the Bronx Veterans Administration Hospital in the 1940s.^[1]

References

• Patton, Dennis D (2002), "Three Nobelists who paved the way.", J. Nucl. Med. 43 (3): 25N-28N, 2002 Mar, PMID:11911104, <http://www.ncbi.nlm.nih.gov/pubmed/11911104>
• Kyle, Robert A & Shampo, Marc A (2002), "Rosalyn Yalow--pioneer in nuclear medicine.", Mayo Clin. Proc. 77 (1): 4, 2002 Jan, PMID:11794457, <http://www.ncbi.nlm.nih.gov/pubmed/11794457>
• Raju, T N (1999), "The Nobel chronicles. 1977: Roger Charles Louis Guillemin (b 1924); Andrew Victor Schally (b 1926); Rosalyn S Yalow (b 1921).", Lancet 354 (9188): 1481, 1999 Oct 23, PMID:10543707, <http://www.ncbi.nlm.nih.gov/pubmed/10543707>
• "Festschrift for Rosalyn S. Yalow: hormones, metabolism, and society.", Mt. Sinai J. Med. 59 (2): 95-185, 1992, 1992 Mar, PMID:1574076, <http://www.ncbi.nlm.nih.gov/pubmed/1574076>
• Yalow, R S & Berson, S A (1996), "Immunoassay of endogenous plasma insulin in man. 1960.", Obes. Res. 4 (6): 583-600, 1996 Nov, PMID:8946444, <http://www.ncbi.nlm.nih.gov/pubmed/8946444>
• Straus, E W (1992), "Festschrift for Rosalyn S. Yalow: Hormones, metabolism, and society.", Mt. Sinai J. Med. 59 (2): 95-100, 1992 Mar, PMID:1574075, <http://www.ncbi.nlm.nih.gov/pubmed/1574075>
• Yalow, R S (1992), "The Nobel lectures in immunology. The Nobel Prize for Physiology or Medicine, 1977 awarded to Rosalyn S. Yalow.", Scand. J. Immunol. 35 (1): 1-23, 1992 Jan, PMID:1734492, <http://www.ncbi.nlm.nih.gov/pubmed/1734492>
• Goldsmith, S J (1987), "Georg de Hevesy Nuclear Medicine Pioneer Award Citation--1986. Rosalyn S. Yalow and Solomon A. Berson.", J. Nucl. Med. 28 (10): 1637-9, 1987 Oct, PMID:3309206, <http://www.ncbi.nlm.nih.gov/pubmed/3309206>
• "Nobel Prize in Physiology or Medicine 1977 awarded to Veterans Administration senoior investigators.", American journal of physical medicine 57 (1): 44-5, 1978, 1978 Feb, PMID:345822, <http://www.ncbi.nlm.nih.gov/pubmed/345822>
• Yanaihara, N (1978), "[1977 Nobel Prize winners in medicine and physiology]", Tanpakushitsu Kakusan Koso 23 (3): 232-6, 1978, PMID:349610, <http://www.ncbi.nlm.nih.gov/pubmed/349610>
• Schwartz, I L, "Solomon A. Berson and Rosalyn S. Yalow: a scientific appreciation.", Mt. Sinai J. Med. 40 (3): 284-94, PMID:4351488, <http://www.ncbi.nlm.nih.gov/pubmed/4351488>

External links

• Dr. Yalow's Autobiography

v • d • e Nobel Laureates in Physiology or Medicine
Baruch Blumberg / Daniel Gajdusek (1976) · Roger Guillemin / Andrew V. Schally / Rosalyn Yalow (1977) · Werner Arber / Daniel Nathans / Hamilton O. Smith (1978) · Allan Cormack / Godfrey Hounsfield (1979) · Baruj Benacerraf / Jean Dausset / George Snell (1980) · Roger Sperry / David H. Hubel / Torsten Wiesel (1981) · Sune Bergström / Bengt I. Samuelsson / John Vane (1982) · Barbara McClintock (1983) · Niels Jerne / Georges Köhler / César Milstein (1984) · Michael Brown / Joseph L. Goldstein (1985) · Stanley Cohen / Rita Levi-Montalcini (1986) · Susumu Tonegawa (1987) · James W. Black / Gertrude B. Elion / George H. Hitchings (1988) · J. Michael Bishop / Harold E. Varmus (1989) · Joseph Murray / E. Donnall Thomas (1990) · Erwin Neher / Bert Sakmann (1991) · Edmond Fischer / Edwin G. Krebs (1992) · Richard J. Roberts / Phillip Sharp (1993) · Alfred G. Gilman / Martin Rodbell (1994) · Edward B. Lewis / Christiane Nüsslein-Volhard / Eric F. Wieschaus (1995) · Peter Doherty / Rolf M. Zinkernagel (1996) · Stanley B. Prusiner (1997) · Robert F. Furchgott / Louis Ignarro / Ferid Murad (1998) · Günter Blobel (1999) · Arvid Carlsson / Paul Greengard / Eric Kandel (2000)
Complete roster · 1901–1925 · 1926–1950 · 1951–1975 · 1976–2000 · 2001–present

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .