SAA1

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

Jump to: navigation, search


Serum amyloid A1
Identifiers
Symbol(s) SAA1; SAA; MGC111216; PIG4; TP53I4
External IDs OMIM: 104750 MGI: 98221 Homologene: 69088
RNA expression pattern

Image:PBB GE SAA1 208607 s at tn.png

Image:PBB GE SAA1 214456 x at tn.png

More reference expression data

Orthologs
Human Mouse
Entrez 6288 20208
Ensembl ENSG00000173432 ENSMUSG00000074115
Uniprot P02735 Q64454
Refseq NM_000331 (mRNA)
NP_000322 (protein) 		NM_009117 (mRNA)
NP_033143 (protein)
Location Chr 11: 18.24 - 18.25 Mb Chr 7: 46.61 - 46.61 Mb
Pubmed search [1] [2]

Serum amyloid A1, also known as SAA1, is a human gene.[1]



References

Further reading

  • Kisilevsky R, Tam SP (2002). "Acute phase serum amyloid A, cholesterol metabolism, and cardiovascular disease.". Pediatric pathology & molecular medicine 21 (3): 291-305. doi:10.1080/02770930290056523. PMID 12056504.
  • Sletten K, Husby G, Natvig JB (1976). "The complete amino acid sequence of an amyloid fibril protein AA1 of unusual size (64 residues).". Biochem. Biophys. Res. Commun. 69 (1): 19-25. PMID 1259755.
  • Beach CM, De Beer MC, Sipe JD, et al. (1992). "Human serum amyloid A protein. Complete amino acid sequence of a new variant.". Biochem. J. 282 ( Pt 2): 615-20. PMID 1546977.
  • Betts JC, Edbrooke MR, Thakker RV, Woo P (1991). "The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells.". Scand. J. Immunol. 34 (4): 471-82. PMID 1656519.
  • Zimlichman S, Danon A, Nathan I, et al. (1990). "Serum amyloid A, an acute phase protein, inhibits platelet activation.". J. Lab. Clin. Med. 116 (2): 180-6. PMID 1697614.
  • Steinkasserer A, Weiss EH, Schwaeble W, Linke RP (1990). "Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.". Biochem. J. 268 (1): 187-93. PMID 1971508.
  • Sack GH, Talbot CC (1991). "Highly polymorphic domains of the human serum amyloid A (SAA) gene GSAA1.". Scand. J. Immunol. 33 (4): 485-8. PMID 2017667.
  • Glaser T, Housman D, Lewis WH, et al. (1990). "A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids.". Somat. Cell Mol. Genet. 15 (6): 477-501. PMID 2595451.
  • Woo P, Sipe J, Dinarello CA, Colten HR (1987). "Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.". J. Biol. Chem. 262 (32): 15790-5. PMID 2890635.
  • Kluve-Beckerman B, Dwulet FE, Benson MD (1988). "Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.". J. Clin. Invest. 82 (5): 1670-5. PMID 3183061.
  • Prelli F, Pras M, Frangione B (1988). "Degradation and deposition of amyloid AA fibrils are tissue specific.". Biochemistry 26 (25): 8251-6. PMID 3442653.
  • Kluve-Beckerman B, Long GL, Benson MD (1987). "DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).". Biochem. Genet. 24 (11-12): 795-803. PMID 3800865.
  • Sipe JD, Colten HR, Goldberger G, et al. (1985). "Human serum amyloid A (SAA): biosynthesis and postsynthetic processing of preSAA and structural variants defined by complementary DNA.". Biochemistry 24 (12): 2931-6. PMID 3839415.
  • Sletten K, Husby G (1974). "The complete amino-acid sequence of non-immunoglobulin amyloid fibril protein AS in rheumatoid arthritis.". Eur. J. Biochem. 41 (1): 117-25. PMID 4816450.
  • Ein D, Kimura S, Terry WD, et al. (1972). "Amino acid sequence of an amyloid fibril protein of unknown origin.". J. Biol. Chem. 247 (17): 5653-5. PMID 5055786.
  • Levin M, Franklin EC, Frangione B, Pras M (1972). "The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils.". J. Clin. Invest. 51 (10): 2773-6. PMID 5056669.
  • Møyner K, Sletten K, Husby G, Natvig JB (1980). "An unusually large (83 amino acid residues) amyloid fibril protein AA from a patient with Waldenström's macroglobulinaemia and amyloidosis.". Scand. J. Immunol. 11 (5): 549-54. PMID 6155694.
  • Parmelee DC, Titani K, Ericsson LH, et al. (1982). "Amino acid sequence of amyloid-related apoprotein (apoSAA1) from human high-density lipoprotein.". Biochemistry 21 (14): 3298-303. PMID 7115671.
  • Badolato R, Wang JM, Murphy WJ, et al. (1994). "Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.". J. Exp. Med. 180 (1): 203-9. PMID 7516407.
  • Badolato R, Johnston JA, Wang JM, et al. (1995). "Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.". J. Immunol. 155 (8): 4004-10. PMID 7561109.
 This protein-related article is a stub. You can help WikiDoc by expanding it.

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

Retrieved from "http://en.wikidoc.org/index.php/SAA1"
Personal tools