SLC5A3
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| Solute carrier family 5 (inositol transporters), member 3
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| Identifiers | ||||||||||||||
| Symbol(s) | SLC5A3; SMIT; SMIT2 | |||||||||||||
| External IDs | OMIM: 600444 MGI: 1858226 Homologene: 31412 | |||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 6526 | 53881
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| Refseq | NM_006933 (mRNA) NP_008864 (protein) | NM_017391 (mRNA) NP_059087 (protein) | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
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Solute carrier family 5 (inositol transporters), member 3, also known as SLC5A3, is a human gene.[1]
See also
References
Further reading
- Kwon HM, Yamauchi A, Uchida S, et al. (1992). "Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein.". J. Biol. Chem. 267 (9): 6297-301. PMID 1372904.
- Berry GT, Mallee JJ, Kwon HM, et al. (1995). "The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21.". Genomics 25 (2): 507-13. PMID 7789985.
- Berry GT, Mallee JJ, Blouin JL, Antonarakis SE (1996). "The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene.". Cytogenet. Cell Genet. 73 (1-2): 77-8. PMID 8646889.
- Mallee JJ, Atta MG, Lorica V, et al. (1998). "The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter.". Genomics 46 (3): 459-65. doi:10.1006/geno.1997.5055. PMID 9441750.
- Porcellati F, Hlaing T, Togawa M, et al. (1998). "Human Na(+)-myo-inositol cotransporter gene: alternate splicing generates diverse transcripts.". Am. J. Physiol. 274 (5 Pt 1): C1215-25. PMID 9612208.
- Rim JS, Atta MG, Dahl SC, et al. (1998). "Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region.". J. Biol. Chem. 273 (32): 20615-21. PMID 9685419.
- Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311-9. doi:10.1038/35012518. PMID 10830953.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711-8. doi:10.1101/gr.2435604. PMID 15342556.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
- Thangaraju M, Gopal E, Martin PM, et al. (2007). "SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.". Cancer Res. 66 (24): 11560-4. doi:10.1158/0008-5472.CAN-06-1950. PMID 17178845.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
