Sarcoma
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| Sarcoma Classification and external resources | |
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WikiDoc Resources for Sarcoma | |
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Most recent articles on Sarcoma | |
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Ongoing Trials on Sarcoma at Clinical Trials.gov Clinical Trials on Sarcoma at Google
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US National Guidelines Clearinghouse on Sarcoma
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Directions to Hospitals Treating Sarcoma Risk calculators and risk factors for Sarcoma
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Causes & Risk Factors for Sarcoma | |
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Overview
A sarcoma (from the Greek 'sarx' meaning "flesh") is a cancer of the connective or supportive tissue (bone, cartilage, fat, muscle, blood vessels) and soft tissue. This is in contrast to carcinomas, which are of epithelial origin (breast, colon, pancreas, and others).
Classification
Sarcomas are given a number of different names, based on the type of tissue from which they arise. For example, osteosarcoma arises from bone, chondrosarcoma arises from cartilage, and leiomyosarcoma arises from smooth muscle. Sarcomas strike people in all age ranges, but they are very rare, accounting for only 1% of all cases of cancer.[1] Soft tissue sarcomas, such as leiomyosarcoma, chondrosarcoma, and gastrointestinal stromal tumor (GIST), are more common in adults than in children. GIST is the most common form of sarcoma, with approximately 3000-3500 cases per year in the United States.[1] This should be compared with breast cancer, with approximately 200,000 cases per year in North America.[1] Bone sarcomas, such as osteosarcoma and Ewing's sarcoma, are more common in children than in adults. These tumors most commonly strike adolescents and young adults between the ages of 12 and 25. In addition to being named based on the tissue of origin, sarcomas are also assigned a grade, such as low grade or high grade. Low grade sarcomas are usually treated surgically, although sometimes radiation therapy or chemotherapy are used. High grade sarcomas are more frequently treated with chemotherapy. Since these tumors are more likely to undergo metastasis (spreading to distant sites), these tumors are treated more aggressively. Childhood sarcomas are almost always treated with a combination of surgery and chemotherapy, and radiation is frequently used as well. The recognition that childhood sarcomas are sensitive to chemotherapy has dramatically improved the survival of patients. For example, in the era before chemotherapy, long term survival for patients with localized osteosarcoma was only approximately 20%, but now has risen to 60-70%.[1]
Types of sarcoma
(ICD-O codes are provided where available.)
- Askin's Tumor (8803/3)
- Chondrosarcoma (9220/3-9240/3)
- Ewing's (9260/3) - PNET (9473/3)
- Malignant Hemangioendothelioma (9130/3)
- Malignant Schwannoma (9560/3-9561/3)
- Osteosarcoma (9180/3-9190/3)
- Soft tissue sarcomas, including:
- Alveolar soft part sarcoma (9581/3)
- Angiosarcoma (9120/3)
- Cystosarcoma Phylloides[3]
- Dermatofibrosarcoma (8832/3-8833/3)
- Desmoid Tumor (8821/1-8822/1)
- Desmoplastic small round cell tumor (8806/3)
- Epithelioid Sarcoma (8804/3)
- Extraskeletal chondrosarcoma (9220/3)
- Extraskeletal osteosarcoma (9180/3)
- Fibrosarcoma (8810/3)
- Hemangiopericytoma (9150)
- Hemangiosarcoma (9120/3)
- Kaposi's sarcoma (9140/3)
- Leiomyosarcoma (8890/3-8896/3)
- Liposarcoma (8850/3-8858/3)
- Lymphangiosarcoma (9170-9175)
- Lymphosarcoma
- Malignant fibrous histiocytoma (8830/3)
- Neurofibrosarcoma (9540/3)
- Rhabdomyosarcoma (8900-8920)
- Synovial sarcoma (9040/3-9043/3)
References
External links
- Sarcoma at the Open Directory Project
da:Sarkom de:Sarkomfa:سارکوما fr:Sarcome it:Sarcoma he:סרקומה nl:Sarcoom ja:肉腫 no:Benvevskreftsv:Sarkomur:لحمومہ
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
