Schmorl's nodes

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Schmorl's nodes
Classification and external resources
ICD-10 M51.4
ICD-9 722.30
DiseasesDB 32386

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Schmorl's nodes

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Overview

Schmorl's nodes are protrusions of the cartilage of the intervertebral disc through the vertebral body endplate and into the adjacent vertebra. [1]

Presentation

The protrusions may contact the marrow of the vertebra, leading to inflammation. The protrusions are also associated with necrosis of the vertebral bone and the question of whether these protrusions and inflammation cause the necrosis, or whether the cartilage migrates into areas that have become necrotic due to other conditions, is under investigation.

They may or may not be symptomatic, and their etiological significance for back pain is controversial.

Diagnosis

Schmorl's nodes can be detected radiographically, although they can be imaged better by CT or MRI.

Causes

It is believed that Schmorl's nodes develop following back trauma, although this is incompletely understood.

Other reports indicate someone can be born with Schmorl's nodes.

Incidence/prevalence

Schmorl's nodes are found in 40 - 75% of autopsies.

Eponym

Schmorl's nodes are named for German pathologist Christian Georg Schmorl (1861-1932)[1].

References

  • McFadden KD, Taylor JR (1989). "End-plate lesions of the lumbar spine". Spine 14 (8): 867-9. PMID 2781398.
  • Peng B, Wu W, Hou S, Shang W, Wang X, Yang Y (2003). "The pathogenesis of Schmorl's nodes". The Journal of bone and joint surgery. British volume 85 (6): 879-82. PMID 12931811.
  • Takahashi K, Miyazaki T, Ohnari H, Takino T, Tomita K (1995). "Schmorl's nodes and low-back pain. Analysis of magnetic resonance imaging findings in symptomatic and asymptomatic individuals". European spine journal 4 (1): 56-9. PMID 7749909.


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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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