Sodium salicylate

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Sodium salicylate
Image:SodiumSalicylate.png
IUPAC name Sodium salicylate
Other names Salsonin, Monosodium salicylate, Sodium o-hydroxybenzoate, Sodium 2-hydroxybenzoate, Salicylic acid sodium salt, Monosodium 2-hydroxybenzoate, Diuratin, ...
Identifiers
CAS number 54-21-7
PubChem 5900
EINECS number 200-198-0
KEGG D00566
RTECS number VO5075000
SMILES [Na+].O=C([O-])c1ccccc1O
InChI InChI=1/C7H6O3.Na/c8-6-4-2-1- 3-5(6)7(9)10;/h1-4,8H,(H,9,10); /q;+1/p-1/fC7H5O3.Na/q-1;m
Properties
Molecular formula C7H5NaO3
Molar mass 160.11 g/mol
Appearance White crystals
Melting point

200 °C

Solubility in water ~ 1000 g/l at 20 °C
Hazards
Main hazards Harmful
NFPA 704

1
1
0
 
R-phrases R22, R36/37/38
S-phrases S24/25, S26, S36/37/39
Autoignition
temperature
> 250 °C
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure.

It is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells [1][2][3] and also necrosis [4]. It is also a potential replacement for aspirin for people sensitive to it.

External links



Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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