Somatostatin receptors

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somatostatin receptor 1
Identifiers
Symbol	SSTR1
Entrez	6751
HUGO	11330
OMIM	182451
RefSeq	NM_001049
UniProt	P30872
Other data
Locus	Chr. 14 q13

somatostatin receptor 2
Identifiers
Symbol	SSTR2
Entrez	6752
HUGO	11331
OMIM	182452
RefSeq	NM_001050
UniProt	P30874
Other data
Locus	Chr. 17 q24

somatostatin receptor 3
Identifiers
Symbol	SSTR3
Entrez	6753
HUGO	11332
OMIM	182453
RefSeq	NM_001051
UniProt	P32745
Other data
Locus	Chr. 22 q13.1

somatostatin receptor 4
Identifiers
Symbol	SSTR4
Entrez	6754
HUGO	11333
OMIM	182454
RefSeq	NM_001052
UniProt	P31391
Other data
Locus	Chr. 20 p11.2

somatostatin receptor 5
Identifiers
Symbol	SSTR5
Entrez	6755
HUGO	11334
OMIM	182455
RefSeq	NM_001053
UniProt	P35346
Other data
Locus	Chr. 16 p13.3

WikiDoc Resources for Somatostatin receptors
Articles
Most recent articles on Somatostatin receptors Most cited articles on Somatostatin receptors Review articles on Somatostatin receptors Articles on Somatostatin receptors in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Somatostatin receptors Images of Somatostatin receptors Photos of Somatostatin receptors Podcasts & MP3s on Somatostatin receptors Videos on Somatostatin receptors
Evidence Based Medicine
Cochrane Collaboration on Somatostatin receptors Bandolier on Somatostatin receptors TRIP on Somatostatin receptors
Clinical Trials
Ongoing Trials on Somatostatin receptors at Clinical Trials.gov Trial results on Somatostatin receptors Clinical Trials on Somatostatin receptors at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Somatostatin receptors NICE Guidance on Somatostatin receptors NHS PRODIGY Guidance FDA on Somatostatin receptors CDC on Somatostatin receptors
Books
Books on Somatostatin receptors
News
Somatostatin receptors in the news Be alerted to news on Somatostatin receptors News trends on Somatostatin receptors
Commentary
Blogs on Somatostatin receptors
Definitions
Definitions of Somatostatin receptors
Patient Resources / Community
Patient resources on Somatostatin receptors Discussion groups on Somatostatin receptors Patient Handouts on Somatostatin receptors Directions to Hospitals Treating Somatostatin receptors Risk calculators and risk factors for Somatostatin receptors
Healthcare Provider Resources
Symptoms of Somatostatin receptors Causes & Risk Factors for Somatostatin receptors Diagnostic studies for Somatostatin receptors Treatment of Somatostatin receptors
Continuing Medical Education (CME)
CME Programs on Somatostatin receptors
International
Somatostatin receptors en Espanol Somatostatin receptors en Francais
Businness
Somatostatin receptors in the Marketplace Patents on Somatostatin receptors
Experimental / Informatics
List of terms related to Somatostatin receptors

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There are five known somatostatin receptors:^[1]

• SST₁ (SSTR1)
• SST₂ (SSTR2)
• SST₃ (SSTR3)
• SST₄ (SSTR4)
• SST₅ (SSTR5)

All are G protein-coupled seven transmembrane receptors.

References

External links

• IUPHAR Receptor Database - Somatostatin Receptors
• MeSH Somatostatin+Receptor

v • d • e Transmembrane receptor: G protein-coupled receptors
Class A: Rhodopsin like	Acetylcholine (M1, M2, M3, M4, M5) - Adrenergic (α1 (A, B, D), α2 (A, B, C), β1, β2, β3) - Adrenomedullin - Anaphylatoxin (C3a, C5a) - Angiotensin (1, 2) - Apelin - Bile acid - Bombesin (BRS3, GRPR, NMBR) - Bradykinin (B1, B2) - Cannabinoid (CB1, CB2) - Chemokine - Cholecystokinin (A, B) - Dopamine (D1, D2, D3, D4, D5) - Eicosanoid (CysLT (1, 2), LTB4 (1, 2), FPRL1, OXE, Prostaglandin ((DP (1, 2), EP (1, 2, 3, 4), PGF, Prostacyclin, Thromboxane) - EBI2 - Endothelin (A, B) - Estrogen - Formyl peptide (1, L1, L2) - Free fatty acid (1, 2, 3, 4) - FSH - Galanin (1, 2, 3) - Gonadotropin-releasing hormone (1, 2) - GPR (1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 79, 82, 83, 84, 85, 87, 88, 92, 101, 103, 119, 120, 132, 135, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 172, 173, 174, 176, 182) - Ghrelin - Histamine (H1, H2, H3, H4) - Kisspeptin - Luteinizing hormone/choriogonadotropin - Lysophospholipid (1, 2, 3, 4, 5, 6, 7, 8) - MAS (1, 1L, D, E, F, G, X1, X2, X3, X4) - Melanocortin (1, 2, 3, 4, 5) - MCHR (1, 2) - Melatonin (1A, 1B)- Motilin - Neuromedin (B, U (1, 2)) - Neuropeptide (B/W (1, 2), FF (1, 2), S, Y (1, 2, 4, 5)) - Neurotensin (1, 2) - Opioid (Delta, Kappa, Mu, Nociceptin, but not Sigma) - Olfactory - Opsin (3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) - Orexin (1, 2) - Oxytocin - Oxoglutarate - PAF - Prokineticin (1, 2) - Prolactin-releasing peptide - Protease-activated (1, 2, 3, 4) - Purinergics (Adenosine (A1, A2a, A2b, A3), P2Y, (1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)) - Relaxin (1, 2, 3, 4) - Somatostatin (1, 2, 3, 4, 5) - Serotonin, all but 5-HT3 (5-HT1 (A, B, D, E, F), 5-HT2 (A, B, C), 5-HT (4, 5A, 6, 7)) - SREB - Succinate - TAAR (1, 2, 3, 5, 6, 8, 9) - Tachykinin (1, 2, 3) - Thyrotropin - Thyrotropin-releasing hormone - Urotensin-II - Vasopressin (1A, 1B, 2)
Class B: Secretin like	Brain-specific angiogenesis inhibitor (1, 2, 3) - Cadherin (1, 2, 3) - Calcitonin - CD97 - Corticotropin-releasing hormone (1, 2) - EMR (1, 2, 3) - Glucagon (GR, GIPR, GLP1R, GLP2R) - Growth hormone releasing hormone - PACAPR1- GPR (56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 157) - Latrophilin (1, 2, 3, ELTD1) - Parathyroid hormone (1, 2) - Secretin - Vasoactive intestinal peptide (1, 2)
Class C: Metabotropic glutamate / pheromone	Calcium-sensing receptor - GABA B (1, 2) - Glutamate receptor (Metabotropic glutamate (1, 2, 3, 4, 5, 6, 7, 8)) - GPRC6A - GPR (156, 158, 179) - RAIG (1, 2, 3, 4) - Taste receptors (TAS1R (1, 2, 3) TAS2R (1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 38, 39, 40, 41, 43, 44, 45, 46, 47, 48, 49, 50))
Frizzled / Smoothened	Frizzled (1, 2, 3, 4, 5, 6, 7, 8, 9, 10) - Smoothened

v • d • e Neuropeptide receptors
Hypothalamic hormone receptors	CRH - FSH - LHRH - TRH - Somatostatin
Pituitary hormone receptors	Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - Type I cytokine receptor (GH, Prolactin) - TSH
Other hormone receptors	Atrial natriuretic factor - Calcitonin - Cholecystokinin (A, B) - VIP
Opioid receptors	Delta - Kappa - Mu - Sigma (1, 2) - Nociceptin
Other neuropeptide receptors	Angiotensin - Bradykinin (B1, B2) / Tachykinin (TACR1) - Calcitonin gene-related peptide - Galanin - GPCR neuropeptide (B/W, FF, S, Y) - Neurotensin

v • d • e WikiDoc Research Resources for Somatostatin receptors
Articles on Somatostatin receptors	Most recent articles on Somatostatin receptors • Most cited articles on Somatostatin receptors • Review articles on Somatostatin receptors • Articles on Somatostatin receptors in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Somatostatin receptors	Powerpoint slides on Somatostatin receptors • Images of Somatostatin receptors • Photos of Somatostatin receptors • Podcasts & MP3s on Somatostatin receptors • Videos on Somatostatin receptors
Evidence Based Medicine Regarding Somatostatin receptors	Cochrane Collaboration on Somatostatin receptors • Bandolier on Somatostatin receptors • TRIP on Somatostatin receptors
Cost Effectiveness of Somatostatin receptors	Cost Effectiveness of Somatostatin receptors
Clinical Trials Involving Somatostatin receptors	Ongoing Trials on Somatostatin receptors at Clinical Trials.gov • Trial results on Somatostatin receptors • Clinical Trials on Somatostatin receptors at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Somatostatin receptors	US National Guidelines Clearinghouse on Somatostatin receptors • NICE Guidance on Somatostatin receptors • NHS PRODIGY Guidance • FDA on Somatostatin receptors • CDC on Somatostatin receptors
Textbook Information on Somatostatin receptors	Books and Textbook Information on Somatostatin receptors
Pharmacology Resources on Somatostatin receptors	Dosing of Somatostatin receptors • Drug interactions with Somatostatin receptors • Side effects of Somatostatin receptors • Allergic reactions to Somatostatin receptors • Overdose information on Somatostatin receptors • Carcinogenicity information on Somatostatin receptors • Somatostatin receptors in pregnancy • Pharmacokinetics of Somatostatin receptors •
Genetics, Pharmacogenomics, and Proteinomics of Somatostatin receptors	Genetics of Somatostatin receptors • Pharmacogenomics of Somatostatin receptors • Proteomics of Somatostatin receptors
Newstories on Somatostatin receptors	Somatostatin receptors in the news • Be alerted to news on Somatostatin receptors • News trends on Somatostatin receptors
Commentary on Somatostatin receptors	Blogs on Somatostatin receptors
Patient Resources on Somatostatin receptors	Patient resources on Somatostatin receptors • Discussion groups on Somatostatin receptors • Patient Handouts on Somatostatin receptors • Directions to Hospitals Treating Somatostatin receptors • Risk calculators and risk factors for Somatostatin receptors
Healthcare Provider Resources on Somatostatin receptors	Symptoms of Somatostatin receptors • Causes & Risk Factors for Somatostatin receptors • Diagnostic studies for Somatostatin receptors • Treatment of Somatostatin receptors
Continuing Medical Education (CME) Programs on Somatostatin receptors	CME Programs on Somatostatin receptors
International Resources on Somatostatin receptors	Somatostatin receptors en Espanol • Somatostatin receptors en Francais
Business Resources on Somatostatin receptors	Somatostatin receptors in the Marketplace • Patents on Somatostatin receptors
Informatics Resources on Somatostatin receptors	List of terms related to Somatostatin receptors

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .