Somitomere
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| Somitomere | ||
|---|---|---|
| Carnegie stage | 11 | |
| Days | third gestational week | |
| Precursor | paraxial mesoderm | |
| Gives rise to | somites | |
In the developing vertebrate embryo, the somitomeres are loose masses of paraxial mesoderm derived cells that form along each side of the neural tube towards the end of the third gestational week. The approximately 50 pairs of somitomeres begin developing in the cranial (head) region, continuing in a caudal (tail) direction until the end of week four.
Development
The first seven somitomeres give rise to the striated muscles of the face, jaws, and throat.
The remaining somitomeres, likely driven by periodic expression of the hairy gene, begin expressing adhesion proteins such as N-cadherin and fibronectin, compact, and bud off forming somites. The somites give rise to the vertebral column (sclerotome), associated muscles (myotome), and overlying dermis (dermatome).
External links
- Swiss embryology (from UL, UB, and UF) hdisqueembry/triderm07 - look for Fig. 16
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
