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Subgenual area 25)
Brodmann area 25 (BA25) is an area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics.
It is also called the subgenual area or area subgenualis.
It is the 25th "Brodmann area" defined by Korbinian Brodmann (thus its name).
BA25 is located in the cingulate region as a narrow band in the caudal portion of the subcallosal area adjacent to the paraterminal gyrus. The posterior parolfactory sulcus separates the paraterminal gyrus from BA25. Rostrally it is bound by the prefrontal area 11 of Brodmann. [1]
History
Brodman described this area as it is labeled now in 1909. Originally in 1905, Brodman labeled the area as part of area 24. In 1909, he divided the area into area 24 and 25.[1]
Pathology
One study has noted that BA25 is metabolically overactive in treatment-resistant depression and has found that chronic deep brain stimulation in the white matter adjacent to the area is a successful treatment for some patients.[1]
Notes and References
See also
| Brain: telencephalon (cerebrum, cerebral cortex, cerebral hemispheres) |
|---|
| Frontal lobe | Precentral gyrus (Primary motor cortex, 4)
Superior frontal gyrus/Frontal eye fields (6, 8, 9), Middle frontal gyrus (46), Inferior frontal gyrus/Broca's area (44-Pars opercularis, 45-Pars triangularis)
Orbitofrontal cortex (10, 11, 12, 47)
Prefrontal cortex, Premotor cortex
Precentral sulcus - Superior frontal sulcus - Inferior frontal sulcus - Olfactory sulcus |
|---|
| Parietal lobe | Somatosensory cortex (Primary (1, 2, 3, 43), Secondary (5)), Precuneus (7m) - Parietal operculum
Parietal lobules (Superior (7l), Inferior (40)), Angular gyrus (39)
Intraparietal sulcus, Marginal sulcus |
|---|
| Occipital lobe | Primary visual cortex (17), (Cuneus, Lingual gyrus, Lateral occipital gyrus (18, 19))
Calcarine fissure |
|---|
| Temporal lobe | Primary auditory cortex (41, 42), Superior temporal gyrus (38, 22/Wernicke's area), Middle temporal gyrus (21), Inferior temporal gyrus (20)
Fusiform gyrus (37) Medial temporal lobe (Amygdala, Parahippocampal gyrus (27, 28, 34, 35, 36) |
|---|
| Cingulate cortex/gyrus | Subgenual area (25), Anterior cingulate (24, 32, 33), Posterior cingulate (23, 31), Retrosplenial cortex (26, 29, 30)
Callosal sulcus |
|---|
| Interlobar sulci/fissures | lateral: Central (frontal+parietal), Lateral (frontal+parietal+temporal), Parietoöccipital
medial: Medial longitudinal, Cingulate (frontal+cingulate), Collateral (temporal+occipital) |
|---|
| White matter tracts | Commissural fibers - Association fibers
Internal capsule (Anterior limb, Genu, Posterior limb), Corona radiata, External capsule, Lamina terminalis, Extreme capsule, Semioval center
Olfactory tract, Terminal stria |
|---|
| Other | Insular cortex
gray: Olfactory bulb, Anterior olfactory nucleus, Basal optic nucleus of Meynert, Substantia innominata, Anterior perforated substance
Corpus striatum - Limbic lobe |
|---|
| Some categorizations are approximations, and some Brodmann areas span gyri. |
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