Sumatriptan
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Synonyms / Brand Names: Sumatriptan Succinate, Sumatriptanum, NP101, triptan, Imigran, Sumatran, Sumax, Imitrex
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
Dosing and Administration
In controlled clinical trials, single doses of 5, 10, or 20 mg of Imitrex Nasal Spray administered into 1 nostril were effective for the acute treatment of migraine in adults. A greater proportion of patients had headache response following a 20-mg dose than following a 5- or 10-mg dose. Individuals may vary in response to doses of Imitrex Nasal Spray. The choice of dose should therefore be made on an individual basis, weighing the possible benefit of the 20-mg dose with the potential for a greater risk of adverse events. A 10-mg dose may be achieved by the administration of a single 5-mg dose in each nostril. There is evidence that doses above 20 mg do not provide a greater effect than 20 mg.
If the headache returns, the dose may be repeated once after 2 hours, not to exceed a total daily dose of 40 mg. The safety of treating an average of more than 4 headaches in a 30-day period has not been established.
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
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Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Sumatriptan
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Publication Resources
Most Recent Articles on Sumatriptan
Review Articles on Sumatriptan
Articles on Sumatriptan in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Sumatriptan
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Trial Resources
Ongoing Trials with Sumatriptan at Clinical Trials.gov
Trial Results with Sumatriptan
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Sumatriptan
Cochrane Collaboration on Sumatriptan
Cost Effectiveness of Sumatriptan
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Media Resources
Powerpoint Slides on Sumatriptan
Images of Sumatriptan
Podcasts & MP3s on Sumatriptan
Videos on Sumatriptan
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Sumatriptan
Discussion Groups on Sumatriptan
Patient Handouts on Sumatriptan
Blogs on Sumatriptan
Sumatriptan in the News
Sumatriptan in the Marketplace
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International Resources
Sumatriptan en Español
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The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
