Table of medication secernated in kidney

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This is a table of medication secernated (secreted) in kidney.

Acid medication are, because of pH parturition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.

Medication Location Acid or base [1] anion or cation[1] Percentage excreted[1]
para-aminohippurate proximal tubule[1] Acid anion
furosemide proximal tubule[1] Acid anion 100-75
glucuronic acid-conjugates proximal tubule[1] Acid
glycine conjugates proximal tubule[1] Acid
indometacin proximal tubule[1] Acid anion
methotrexate proximal tubule[1] Acid 100-75
penicillin proximal tubule[1] Acid anion 75-50
(benzylpenicillin)
probenecid proximal tubule[1] Acid anion
sulphate conjugates proximal tubule[1] Acid
thiazide diuretics proximal tubule[1] Acid
uric acid proximal tubule[1] Acid
amiloride proximal tubule[1] Base cation
dopamine proximal tubule[1] Base
histamine proximal tubule[1] Base
mepacrine proximal tubule[1] Base
morphine proximal tubule[1] Base cation
pethidine proximal tubule[1] Base
quaternary ammonium compounds proximal tubule[1] Base
quinine proximal tubule[1] Base cation
5 hydroxytryptamine proximal tubule[1] Base
triamterene proximal tubule[1] Base
gentamicin 100-75
atenolol 100-75
digoxin 100-75
cimetidine cation 75-50
tetracycline 75-50
(oxytetracycline)
neostigmine 75-50
propantheline ~50
tubocurarine ~50
acetazolamide proximal tubule[1] anion
chlorothiazide proximal tubule[1] anion
saccharin proximal tubule[1] anion
salicylate proximal tubule[1] anion
atropine proximal tubule[1] cation
NMN proximal tubule[1] cation
paraquat proximal tubule[1] cation
procainamide proximal tubule[1] cation
tetraethylammonium proximal tubule[1] cation
chlorpromazine proximal tubule[1] cation

References

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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