Thyroxine
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| Thyroxine | |
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| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| SMILES | NC(Cc1cc(I)c(Oc2cc(I)c(O) c(I)c2)c(I)c1)C(O)=O |
| Properties | |
| Molecular formula | C15H11I4NO4 |
| Molar mass | 776.87 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
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Thyroxine, or 3:5,3':5' tetraiodothyronine (often abbreviated as T4) is the major hormone secreted by the follicular cells of the thyroid gland.
T4 is transported in blood, with 99.95% of the secreted T4 being protein bound, principally to thyroxine binding globulin (TBG) and to a lesser extent to transthyretin and serum albumin.
T4 is involved in controlling the rate of metabolic processes in the body and influencing physical development.
Note: Thyroxine is a prohormone and a reservoir for the active thyroid hormone triiodothyronine (T3), T4 being converted as required in the tissues by deiodinases.
Type II deiodinase converts T4 into T3.
The "D" isomer is called "Dextrothyroxine"[1] and is used as a lipid modifying agent.[2]
The half life of thyroxine once released into the blood circulatory system is about 1 week
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References
ar:ثيروكسينbg:Тироксин cs:Thyroxin da:Thyroxin de:Thyroxin et:Türoksiinhe:תירוקסין it:Tiroxina lt:Tiroksinas nl:Thyroxinefi:Tyroksiini sv:Tyroxin
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
