Transmarginal inhibition
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| Transmarginal inhibition Classification and external resources |
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Transmarginal inhibition, or TMI, is an organism's response to overwhelming stimuli.
Research
Ivan Pavlov enumerated details of TMI on his work of conditioning animals to pain. He found that organisms responded had different levels of tolerance. He commented "that the most basic inherited difference among people was how soon they reached this shutdown point and that the quick-to-shut-down have a fundamentally different type of nervous system."[1]
Patients who have reached this shutdown point often become socially dysfunctional or develop one of several personality disorders. Often patients who dissociate during and after the experience, will more easily dissociate or shut down during stressful or painful experiences, and may experience post traumatic stress disorder for the remainder of their lives.
There are three stages passed through for state of TMI to be reached. The first, equivalent phase, is when the response matches the stimuli, which is considered the normal baseline behavior. The paradoxical phase occurs when small stimuli receive major response and a major stimuli elicit small responses. Finally, the ultra-paradoxical stage where negative stimulation results in positive responses and vice versa. Additional research on these phases was done by William Sargant in his work on shell-shocked servicemen.
An organism can progress through these stages by increased stimulation, random negative stimulation, reversing positive and negative stimulation, or physically debilitating the organism.
As observed by Pavlov, tolerance of stimulation varies greatly between individuals. Highly sensitive persons may be overstimulated by the loud volumes in a movie theater or the background confusion of a large social gathering. Other individuals will find those same stimulations as ideal stimulation levels, or even understimulating.
Use in mental conditioning
The sudden conversion methods of mental conditioning rely heavily on TMI. Of the ten elements of control (environment control, physical fatigue, mental fatigue, tension or uncertainty, confession, superstimulation, crisis, euphoria, proselytization, and restimulation), six can be seen as stimulation toward TMI. Organizations that practice sudden conversion, such as military boot camps, prisons, and extreme psychiatric treatments, often have individuals enter TMI states which may result in permanent psychological damage.
References
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

