Upper motor neuron lesion
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| Upper motor neuron lesion Classification and external resources | |
| The motor tract. | |
| DiseasesDB | 27852 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
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An upper motor neuron lesion is a lesion of the neural pathway above the anterior horn cell or motor nuclei of the cranial nerves. This is in contrast to a lower motor neuron lesion, which affects nerve fibers traveling from the anterior horn of the spinal cord to the relevant muscle(s).
Symptoms
- Spastic increase in tone in the extensor muscles (lower limbs) or flexor muscles (upper limbs)
- Clasp-knife response where initial resistance to movement is followed by relaxation
- Weakness in the flexors (lower limbs) or extensors (upper limbs),[1] but no muscle wasting
- Brisk tendon jerk reflexes
- Babinski sign positive, where the big toe is raised rather than curled downwards on stimulation of the sole of the foot
Corticospinal/pyramidal tract
These are the neural tracts which descend in the spinal cord, in the lateral columns, carrying signals for voluntary movement of skeletal muscle. These nerve fibres usually originate in the cerebral cortex, then gather in the internal capsule before crossing over to the opposite side (decussation) in the medulla oblongata and proceeding down the spinal cord to meet lower motor neurons in the anterior horn.
See also
References
External links
- http://www.med.yale.edu/caim/cnerves/cn7/cn7_13.html
- http://www.lib.mcg.edu/edu/eshuphysio/program/section8/8ch3/s8ch3_34.htm
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

