Renal agenesis
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| Renal agenesis Classification and external resources | |
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| Renal abscess also renal agenesis with unicornuate uterus: Meyer-Rokitanski-Kuster-Hauser syndrome. A 38 year old female with pyelonephritis which is resistant to antibiotics. 1. Multiple renal abscesses involving the left kidney, the largest measuring 4 cm x 3.5 cm. 2. Right renal agenesis with possible unicornuate uterus. 3. Small bilateral pleural effusions. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology | |
| ICD-10 | Q60.0-Q60.2 |
| ICD-9 | 753.0 |
| OMIM | 191830 |
| DiseasesDB | 11252 |
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Renal agenesis is the absence of one (unilateral) or both (bilateral) kidneys at birth.
Bilateral renal agenesis
Bilateral renal agenesis is uncommon and is a serious condition. See Potter syndrome.
Bilateral Renal Agenesis is the absence of both kidneys at birth. It is a genetic disorder characterized by a failure of the kidneys to develop in a fetus. This absence of kidneys causes a deficiency of amniotic fluid (Oligohydramnios) in a pregnant woman. Normally, the amniotic fluid acts as a cushion for the developing fetus. When there is an insufficient amount of this fluid, compression of the fetus may occur resulting in further malformations of the baby.
This disorder is more common in infants born of a parent who has a kidney malformation, particularly the absence of one kidney (unilateral renal agenesis). Studies have proven that unilateral renal agenesis and bilateral renal agenesis are genetically related. 1 in 3 infants with this congenital defect are still born. Most infants that are born alive do not live beyond four hours.
Unilateral renal agenesis
This is much more common, but is not usually of any major concern, as long as the other kidney is healthy. The odds of a person being born with this condition are roughly 1 in 5000. Adults with unilateral renal agenesis have considerably higher chances of hypertension and high blood pressure. Most contact sports would be advised against.
External links
Congenital malformations and deformations of genital organs and urinary system (Q50-Q64, 752-753) | |
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| Genital organs (overview) | female: Uterine malformation - Mullerian agenesis - Uterine didelphys - Clitoromegaly
male: Cryptorchidism - Hypospadias - Chordee - Monorchism - Micropenis - Penile agenesis Pseudohermaphroditism |
| Urinary system | kidney/ureter: Renal agenesis/Potter syndrome, Papillorenal syndrome - cystic (Polycystic kidney disease, Meckel syndrome, Multicystic dysplastic kidney) - Ectopic ureter - Horseshoe kidney - Renal ectopia
bladder/urethra: Epispadias - Bladder exstrophy urachus: Urachal cyst |
| See also non-congenital reproductive and urinary conditions (N, 580-629) | |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
