Zimmerman-Laband syndrome
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| Zimmerman-Laband syndrome Classification and external resources | |
| ICD-10 | GroupMajor.minor |
|---|---|
| ICD-9 | xxx |
| OMIM | 135500 |
| DiseasesDB | 34028 |
Zimmerman-Laband syndrome (ZLS),[1] also known as Laband's Syndrome,[1] is an extremely rare[1] congenital genetically inherited syndrome. The disease is considered to be inherited in a autosomal dominant fashion. Symptoms include gingival fibromatosis, associated with hypoplasia of the distal phalanges, nail dysplasia, joint hypermobility, and sometimes hepatosplenomegaly. The nose and pinnas are usually large and poorly developed, which gives the individuals with the syndrome abnormal facial characteristics. Mental retardation may also occur.[1][1] Both males and females are equally affected. Gingival fibromatosis is usually present at birth or appears short after.[1][1] The term Zimmermann-Laband was coined by Carl Jacob Witkop in 1971.[1]
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
