Zona glomerulosa
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| Zona glomerulosa | |
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| Layers of cortex. | |
| Gray's | subject #277 1278 |
| Dorlands/Elsevier | z_01/12869730 |
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The zona glomerulosa of the adrenal gland is the most superficial layer of the adrenal cortex, lying directly beneath the adrenal gland's capsule. Its cells are ovoid in shape and are arranged in clusters or arches (glomus is Latin for "ball").
In response to increased potassium levels or decreased blood flow to the kidneys, cells of the zona glomerulosa secrete the mineralocorticoid aldosterone into the blood as part of the renin-angiotensin system. Aldosterone regulates the body's concentration of electrolytes, primarily sodium and potassium, by acting on the distal convoluted tubule of kidney nephrons to:
- increase sodium reabsorption
- increase potassium excretion
- increase water reabsorption through osmosis
The enzyme aldosterone synthase acts in this location.
External links
- Histology at BU 14502loa
- Anatomy Atlases - Microscopic Anatomy, plate 15.292 - "Adrenal Gland"
Endocrine system > Adrenal glands | |
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| Medulla | Chromaffin cells |
| Cortex | Zona glomerulosa • Zona fasciculata • Zona reticularis |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
