Zones of the lung

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The zones of the lung proposed by West in 1964,^[1] divide the lung into three vertical regions, based upon the relationship between the pressure in the alveoli (PA), in the arteries (Pa), and the veins (Pv):

• #1: alveolar > arterial > venous
• #2: arterial > alveolar > venous
• #3: arterial > venous > alveolar

The ventilation/perfusion ratio is higher in zone #1 (the apex of lung when a person is standing) than it is in zone #3 (the base of lung.)

References

External links

• Physiology at MCG 4/4ch4/s4ch4_28
• Description at anaesthetist.com
• Animated diagram at sites.fasthosts.com

v • d • e Respiratory system, physiology: respiratory physiology
Volumes	lung volumes - vital capacity - functional residual capacity - respiratory minute volume - closing capacity - dead space - spirometry - body plethysmography - peak flow meter - thoracic independent volume - bronchial challenge test
Airways	ventilation (V) (positive pressure) - breath (inhalation, exhalation) -respiratory rate - respirometer - pulmonary surfactant - compliance - hysteresivity - airway resistance
Blood	pulmonary circulation - perfusion (Q) - hypoxic pulmonary vasoconstriction - pulmonary shunt
Interactions	ventilation/perfusion ratio (V/Q) and scan - zones of the lung - gas exchange - pulmonary gas pressures - alveolar gas equation - hemoglobin - oxygen-haemoglobin dissociation curve (2,3-DPG, Bohr effect, Haldane effect) - carbonic anhydrase (chloride shift) - oxyhemoglobin - respiratory quotient - arterial blood gas - diffusion capacity - Dlco
Control of respiration	pons (pneumotaxic center, apneustic center) - medulla (dorsal respiratory group, ventral respiratory group) - chemoreceptors (central, peripheral) - pulmonary stretch receptors (Hering-Breuer reflex)
Insufficiency	high altitude - oxygen toxicity - hypoxia

v • d • e WikiDoc Research Resources for Zones of the lung (Click show to right to view)
Articles on Zones of the lung	Most recent articles on Zones of the lung • Most cited articles on Zones of the lung • Review articles on Zones of the lung • Articles on Zones of the lung in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Zones of the lung	Powerpoint slides on Zones of the lung • Images of Zones of the lung • Photos of Zones of the lung • Podcasts & MP3s on Zones of the lung • Videos on Zones of the lung
Evidence Based Medicine Regarding Zones of the lung	Cochrane Collaboration on Zones of the lung • Bandolier on Zones of the lung • TRIP on Zones of the lung
Cost Effectiveness of Zones of the lung	Cost Effectiveness of Zones of the lung
Clinical Trials Involving Zones of the lung	Ongoing Trials on Zones of the lung at Clinical Trials.gov • Trial results on Zones of the lung • Clinical Trials on Zones of the lung at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Zones of the lung	US National Guidelines Clearinghouse on Zones of the lung • NICE Guidance on Zones of the lung • NHS PRODIGY Guidance • FDA on Zones of the lung • CDC on Zones of the lung
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Genetics, Pharmacogenomics, and Proteinomics of Zones of the lung	Genetics of Zones of the lung • Pharmacogenomics of Zones of the lung • Proteomics of Zones of the lung
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Healthcare Provider Resources on Zones of the lung	Symptoms of Zones of the lung • Causes & Risk Factors for Zones of the lung • Diagnostic studies for Zones of the lung • Treatment of Zones of the lung
Continuing Medical Education (CME) Programs on Zones of the lung	CME Programs on Zones of the lung
International Resources on Zones of the lung	Zones of the lung en Espanol • Zones of the lung en Francais
Business Resources on Zones of the lung	Zones of the lung in the Marketplace • Patents on Zones of the lung
Informatics Resources on Zones of the lung	List of terms related to Zones of the lung

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .