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WikiDoc Resources for Arteriosclerosis


Most recent articles on Arteriosclerosis

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Articles on Arteriosclerosis in N Eng J Med, Lancet, BMJ


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FDA on Arteriosclerosis

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Books on Arteriosclerosis


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Definitions of Arteriosclerosis

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Directions to Hospitals Treating Arteriosclerosis

Risk calculators and risk factors for Arteriosclerosis

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Symptoms of Arteriosclerosis

Causes & Risk Factors for Arteriosclerosis

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Treatment of Arteriosclerosis

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Arteriosclerosis en Espanol

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Arteriosclerosis in the Marketplace

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List of terms related to Arteriosclerosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; {AE}}

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Arteriosclerosis refers to a hardening of medium and large arteries. The most common form of arteriosclerosis is atherosclerosis.

Historical Perspective


The following terms are similar, yet distinct, in both spelling and meaning, and can be easily confused: arteriosclerosis, arteriolosclerosis, and atherosclerosis. Arteriosclerosis is a general term describing any hardening (and loss of elasticity) of medium or large arteries (from the Greek Arterio, meaning artery, and sclerosis, meaning hardening), arteriolosclerosis is any hardening (and loss of elasticity) of arterioles (small arteries), atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. Therefore, atherosclerosis is a form of arteriosclerosis.



  • Atherosclerosis is the most common form of arteriosclerosis. In atherosclerosis, thickening of the intima with plaques that can contain lipid-laden macrophages ("foam cells"). The plaques contain free lipid (cholesterol, etc.) and are prone to calcification and ulceration.
  • Arteriosclerosis obliterans is typically seen in medium and large arteries of the lower extremity. Characterized by fibrosis of the intima and calcification of the media. The lumen of the vessel may be obliterated or markedly narrowed.
  • Medial calcific sclerosis (Monckeberg’s calcific sclerosis) is seen mostly in the elderly, commonly in arteries of the thyroid and uterus. Characterized by calcification of the internal elastic lamina but without thickening of the intima or narrowing of the vessel lumen.
  • Hyaline arteriolosclerosis refers to thickening of the walls of arterioles by the deposition of hyaline material. Often seen in kidney pathology.



Differentiating Arteriosclerosis from Other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications, and Prognosis


Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies


Medical Therapy




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