Dermatitis herpetiformis secondary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Dermatitis Herpetiformis (also called Duhring's disease), is a chronic itchy rash which is frequently associated with Celiac Disease. The rash is made of papules and vesicles which are present on different parts of the body mostly commonly on neck, trunk, buttocks and knees. It is an autoimmune mediated skin condition, which is IgA mediated reaction and is associated with gluten sensitivity of small bowel. There is presence of antibodies which leads to positive serology test results.

Dermatitis herpetiformis is associated with high prevalence of other autoimmune diseases.

Secondary Prevention

Strict adherence to gluten free diet and dapsone, should improve the symptoms in few days of initiation of treatment. After tapering of dapsone, patient should be instructed to continue gluten free diet because it prevents the reappearance of symptoms and complications of celiac disease [1].


  1. Cardones AR, Hall RP 3rd. Management of dermatitis herpetiformis. Immunol Allergy Clin North Am. 2012 May;32(2):275-81, vi-vii. doi: 10.1016/j.iac.2012.04.007. Epub 2012 Apr 18. PMID: 22560140.

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