Eczema primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.


Primary prevention is the most effective means to avoid complications of eczema. Emolients and consumption of prebiotics and probiotics can prevent the occurrence of this condition. [1] [2] Exclusive breastfeeding in a duration of three to four months has been proven to reduce the risk of acquiring eczema in children ≤ 2 years old.[3]



  1. Macharia WM, Anabwani GM, Owili DM (1991). "Effects of skin contactants on evolution of atopic dermatitis in child[[Primary prevention]] is the most effective means to avoid [[complications]] of eczema. This can be achieved by applying [[emolients]] on the [[skin]], and consumption of [[probiotics]] and [[prebiotics]].ren: a case control study". Trop Doct. 21 (3): 104–6. doi:10.1177/004947559102100305. PMID 1926547. URL–wikilink conflict (help)
  2. Abrahamsson TR, Jakobsson HE, Andersson AF, Björkstén B, Engstrand L, Jenmalm MC (2012). "Low diversity of the gut microbiota in infants with atopic eczema". J Allergy Clin Immunol. 129 (2): 434–40, 440.e1–2. doi:10.1016/j.jaci.2011.10.025. PMID 22153774.
  3. Greer FR, Sicherer SH, Burks AW, COMMITTEE ON NUTRITION. SECTION ON ALLERGY AND IMMUNOLOGY (2019). "The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing of Introduction of Allergenic Complementary Foods". Pediatrics. 143 (4). doi:10.1542/peds.2019-0281. PMID 30886111.
  4. Wollenberg A, Christen-Zäch S, Taieb A, Paul C, Thyssen JP, de Bruin-Weller M; et al. (2020). "ETFAD/EADV Eczema task force 2020 position paper on diagnosis and treatment of atopic dermatitis in adults and children". J Eur Acad Dermatol Venereol. 34 (12): 2717–2744. doi:10.1111/jdv.16892. PMID 33205485 Check |pmid= value (help).
  5. Palmer DJ (2015). "Vitamin D and the Development of Atopic Eczema". J Clin Med. 4 (5): 1036–50. doi:10.3390/jcm4051036. PMC 4470215. PMID 26239464.
  6. Muraro A, Dreborg S, Halken S, Høst A, Niggemann B, Aalberse R; et al. (2004). "Dietary prevention of allergic diseases in infants and small children. Part II. Evaluation of methods in allergy prevention studies and sensitization markers. Definitions and diagnostic criteria of allergic diseases". Pediatr Allergy Immunol. 15 (3): 196–205. doi:10.1111/j.1399-3038.2004.00128.x. PMID 15209950.
  7. Szajewska H, Horvath A (2010). "Meta-analysis of the evidence for a partially hydrolyzed 100% whey formula for the prevention of allergic diseases". Curr Med Res Opin. 26 (2): 423–37. doi:10.1185/03007990903510317. PMID 20001576.
  8. von Berg A, Koletzko S, Grübl A, Filipiak-Pittroff B, Wichmann HE, Bauer CP; et al. (2003). "The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: the German Infant Nutritional Intervention Study, a randomized double-blind trial". J Allergy Clin Immunol. 111 (3): 533–40. doi:10.1067/mai.2003.101. PMID 12642834.
  9. von Berg A, Filipiak-Pittroff B, Krämer U, Link E, Bollrath C, Brockow I; et al. (2008). "Preventive effect of hydrolyzed infant formulas persists until age 6 years: long-term results from the German Infant Nutritional Intervention Study (GINI)". J Allergy Clin Immunol. 121 (6): 1442–7. doi:10.1016/j.jaci.2008.04.021. PMID 18539195.
  10. Kulthanan K, Tuchinda P, Nitiyarom R, Chunharas A, Chantaphakul H, Aunhachoke K; et al. (2021). "Clinical practice guidelines for the diagnosis and management of atopic dermatitis". Asian Pac J Allergy Immunol. 39 (3): 145–155. doi:10.12932/AP-010221-1050. PMID 34246205 Check |pmid= value (help).
  11. Schneider L, Tilles S, Lio P, Boguniewicz M, Beck L, LeBovidge J; et al. (2013). "Atopic dermatitis: a practice parameter update 2012". J Allergy Clin Immunol. 131 (2): 295-9.e1-27. doi:10.1016/j.jaci.2012.12.672. PMID 23374261.