Halo nevus

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Synonyms and keywords: Leukoderma acquisitum centrifugum, Perinevoid vitiligo, Sutton nevus


Halo nevus is a mole that is surrounded by a depigmented ring or 'halo'.[1]:689)


The formation of a halo surrounding a nevi is believed to occur when certain white blood cells called CD8+ T lymphocytes destroy the pigment-producing cells of the skin (melanocytes).[2] The trigger for the autoimmune attack is unknown.[3]

Epidemiology and Demographics

Halo nevi are estimated to be present in approximately 1% of the general population, and All races and sexes are equally susceptible to this disease, although a familial tendency has been reported. The average age of onset is in a person's teenage years.

Risk Factors

Halo Nevi are found to be more prevalent in people with vitiligo, malignant melanoma,[3] or Turner syndrome.


Physical Examination


File:Halo Nevus zoomed.jpg
Photograph of a halo nevus on a face

Halo nevi are named such because they are a mole (nevi) that is surrounded by an area of depigmentation that resembles a halo.


Natural History, Prognosis, and Complications

Sometimes the pale (hypopigmented) areas will spontaneous regress, and pigment returns. Although halo nevi are harmless, it is important to monitor the lesion on regular basis.[5] Any changes in appearance of existing or new halo nevi should be noted. If there is any change in appearance or is associated with pain, itch, and infection, a doctor should be consulted immediately to exclude the possibility of melanoma.


As halo nevi are only of cosmetic significance, no treatment is required,[6] and patients will be asymptomatic.

See also


  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. Mundinger, Gerhard S. (January 16, 2014). "Halo Phenomenon". New England Journal of Medicine. 370 (3): 262–262. doi:10.1056/NEJMicm1306230.
  3. 3.0 3.1 "Halo Nevus - skinsite.com". Retrieved August 4, 2008.
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 "Dermatology Atlas".
  5. "DermaTalk - Halo Nevus".
  6. "CareFair.com - Halo Nevis". Retrieved August 4, 2008.