Scleroderma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]
Overview
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, Raynaud's phenomenon, and symptoms of gastroesophageal reflux disease (GERD). Less common symptoms of scleroderma include shiny skin appearance and restricted movement of affected areas of the skin.
History and Symptoms
The hallmark of scleroderma is sclerodactyly. A positive history of progressive skin tightening and hardening is suggestive of scleroderma. The most common symptoms of scleroderma include skin tightening or induration, Raynaud's phenomenon and symptoms of gastroesophageal reflux disease (GERD).[1]
History
Patients with scleroderma may have a positive history of:
- Progressive skin tightening or hardening[2][3]
- Skin induration affecting fingers and extending proximally (sclerodactyly)[2][3]
- Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's phenomenon)[3]
- Swallowing difficulty[1]
- Heartburn
- Abdominal pain
- Nausea
- Vomiting
- Bloating
- Flatulence
- Altered bowel movements
- Fatigue[4]
- Weakness
- Weight loss
- Musculoskeletal pain
Common Symptoms
Common symptoms of scleroderma include:
- Skin tightening and induration (hardening)[2][3]
- Exaggerated response to cold temperatures or emotional stress causing numbness, pain or color changes in fingers or toes (Raynaud's Phenomenon)[3]
- Non-productive cough[3]
- Chest tightness
- Chest pain
- Joint pain
- Dysphagia[1][3]
- Abdominal pain
- Diarrhea
- Constipation
Less Common Symptoms
Less common symptoms of scleroderma include:
References
- ↑ 1.0 1.1 1.2 Shreiner AB, Murray C, Denton C, Khanna D (2016). "Gastrointestinal Manifestations of Systemic Sclerosis". J Scleroderma Relat Disord. 1 (3): 247–256. doi:10.5301/jsrd.5000214. PMC 5267349. PMID 28133631.
- ↑ 2.0 2.1 2.2 Pogorzelska-Antkowiak A, Antkowiak R (2006). "[Diagnostic and therapeutic problems of scleroderma]". Wiad. Lek. (in Polish). 59 (5–6): 392–5. PMID 17017489.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Hudson M, Fritzler MJ, Baron M (May 2010). "Systemic sclerosis: establishing diagnostic criteria". Medicine (Baltimore). 89 (3): 159–65. doi:10.1097/MD.0b013e3181dde28d. PMID 20453602.
- ↑ Sandusky SB, McGuire L, Smith MT, Wigley FM, Haythornthwaite JA (February 2009). "Fatigue: an overlooked determinant of physical function in scleroderma". Rheumatology (Oxford). 48 (2): 165–9. doi:10.1093/rheumatology/ken455. PMC 2638541. PMID 19106163.