Vitiligo classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Vitiligo can be classified in two clinical subtypes; segmented vitiligo, which affects only 1 segment of the body (face, arm or leg) and non-segmented vitiligo, involving more than 1 segment, such as both knees or both hands.


Characteristics of the Subtypes of Vitiligo
Non-segmental Vitiligo Segmental Vitiligo
Definition Involves both sides of the body, most common type Involves 1 segment of the body (face, arm or leg)
Age Later onset is more common than in childhood More common in childhood
Onset and progression Progressive, with acute episodes Rapid and stabilizes
Hair involvement In later stages Early
Association with other autoimmune conditions Yes No
Common location Areas prone to pressure or friction Face
Response to autologous grafting Good response Relapses
Table adapted from N Engl J Med 2009;360:160-9[1], EDF Vitiligo Guidelines, A. Taieb et al. [2] and J Am Acad Dermatol Mazereeuw-Hautier et al [3]


  1. Taïeb, Alain; Picardo, Mauro (2009). "Vitiligo". New England Journal of Medicine. 360 (2): 160–169. doi:10.1056/NEJMcp0804388. ISSN 0028-4793.
  2. Taieb, A.; Alomar, A.; Böhm, M.; Dell’Anna, M.L.; De Pase, A.; Eleftheriadou, V.; Ezzedine, K.; Gauthier, Y.; Gawkrodger, D.J.; Jouary, T.; Leone, G.; Moretti, S.; Nieuweboer-Krobotova, L.; Olsson, M.J.; Parsad, D.; Passeron, T.; Tanew, A.; van der Veen, W.; van Geel, N.; Whitton, M.; Wolkerstorfer, A.; Picardo, M. (2013). "Guidelines for the management of vitiligo: the European Dermatology Forum consensus". British Journal of Dermatology. 168 (1): 5–19. doi:10.1111/j.1365-2133.2012.11197.x. ISSN 0007-0963.
  3. Juliette Mazereeuw-Hautier, Sophie Bezio, Emmanuel Mahe, Christine Bodemer, Catherine Eschard, Valerie Viseux, Christine Labreze, Patrice Plantin, Sebastien Barbarot, Pierre Vabres, Ludovic Martin, Carle Paul & Jean-Philippe Lacour (2010). "Segmental and nonsegmental childhood vitiligo has distinct clinical characteristics: a prospective observational study". Journal of the American Academy of Dermatology. 62 (6): 945–949. doi:10.1016/j.jaad.2009.06.081. PMID 20466172. Unknown parameter |month= ignored (help)

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